Dr Kehinde Ross
Pharmacy and Biomolecular Sciences
Faculty of Science
Email: O.K.Ross@ljmu.ac.uk
Telephone: 0151 231 2567
@KehindeRoss
ORCID
I am a Reader (Associate Professor) in Molecular and Cellular Biology, having joined LJMU as a lecturer in August 2008. My current research focuses on the role of microRNAs and associated pathways in skin disorders such as psoriasis, eczema, impaired wound healing and alopecia. I also have interdisciplinary collaborations on the development of polymer and peptide nanocarriers for miRNA-directed therapy for inflammatory diseases and cancer. Since November 2022, I have led one of only two inaugural Thematic Doctoral Pathway PhD training programmes at LJMU, titled Transformative Peptide Chemistry for RNA Nanotherapies. This work targets skin disorders as well as brain cancer (glioblastoma, medulloblastoma) and lung cancer.
Since May 2021, I have been the co-lead of the Institute for Health Research Diagnostics and Therapeutics group: https://www.ljmu.ac.uk/research/centres-and-institutes/institute-of-health-research/expertise/diagnostics-and-therapeutics.
Prior to LJMU, I completed postdoctoral research in the Dermatological Sciences laboratory at Newcastle University under the guidance of Professor Nick Reynolds. For my PhD at the University of Sheffield, I studied cytokine signalling proteins associated with inflammatory diseases, under the supervision of Dr François Guesdon and Professor Steve Dower. A year was spent at GSK Stevenage under the supervision of Dr Filippo Volpe.
Research in my laboratory has been supported by the British Skin Foundation, the Cicatricial Alopecia Research Foundation, the Royal Liverpool and Broadgreen Hospitals NHS Trust, the Ministry of Health, Oman.
I have supervised 5 postdoctoral/visiting scientists and over 12 placement students on Nuffield, Erasmus, learned society or independent schemes. I am a member of the Biochemical Society, the British Society for Investigative Dermatology, the British Hair and Nail Society, the Physiological Society, the RNA Society and the European Tissue Repair Society. I am also an affiliate member of the Royal Society of Chemistry.
My teaching activities focus on signal transduction and microRNA. For signalling pathways, I cover receptor tyrosine kinases, G protein-coupled receptors, cytokine receptors and store-operated calcium entry, with structural perspectives where appropriate. For miRNA, I teach the fundamentals of their expression and function, with a focus on wound healing for real-world relevance. I have supervised over 77 undergraduate project students.
A Fellow of the Higher Education Academy (FHEA), I was nominated for the Liverpool Students' Union Amazing Teacher Award in 2011, 2013, 2015 and 2016.
POSTDOCTORAL SUPERVISION
Dr Julian Roberts: May 2009 to Nov 2011
Now: https://gearulabs.com
COMPLETED PhD SUPERVISION
Dr Talhat Chaudhry: Feb. 2019 to Jan. 2023: Director of Studies
Next: Sygnature Discovery
Dr Giulia Scagnetti: Sept. 2018 to Aug. 2022: Co-supervisor
Next: IQVIA
Dr Mujtaba Al-Lawati 2019: Sept. 2015 to Nov. 2019: Director of Studies
Next: Ministry of Health, Oman.
Dr Adam Richardson: July 2015 to Dec. 2018: Director of Studies
Next: Cello Health (now Lumanity). https://lumanity.com/
Dr Adel Mohammed: Jan. 2014 to June 2018: Co-supervisor
Next: Imperial College London
David Farrer (MPhil): May 2010 to March 2012: Director of Studies
Next: NHS Orkney
Degrees
2013, Liverpool John Moores University, United Kingdom, Postgraduate Certificate for Learning and Teaching in Higher Education
2001, University of Sheffield, United Kingdom, PhD
1997, Brunel University, United Kingdom, BSc (Honours)
Academic appointments
Reader in Molecular and Cellular Biology, Pharmacy and Biomolecular Sciences, Liverpool John Moores University, 2020 - present
Senior Lecturer in Biochemistry and Cell Biology, Pharmacy and Biomolecular Sciences, Liverpool John Moores University, 2008 - 2020
Postdoctoral Research Associate, Newcastle University, 2003 - 2008
Postgraduate training
Postdoctoral Research Associate, United Kingdom, Newcastle University, 2003 - 2008
Highlighted publications
Chaudhry T, Coxon CR, Ross K. 2022. Trading places: Peptide and small molecule alternatives to oligonucleotide-based modulation of microRNA expression Drug Discovery Today, 27 DOI Author Url Publisher Url Public Url
Preethi KA, Selvakumar SC, Ross K, Sekar D. 2022. Therapeutic aspect of microRNA inhibition in various types of hypertension and hypertensive complications Gene Reports, 29 :101676-101676 DOI Publisher Url Public Url
Fawcett SA, Al Kassas R, Dykes IM, Hughes AT, Ghali F, Ross K. 2022. A Time to Heal: MicroRNA and Circadian Dynamics in Cutaneous Wound Repair Clinical Science, 136 :579-597 DOI Author Url Publisher Url Public Url
Dykes IM, Ross K. 2021. Restoring the Final Frontier: Exosomal MicroRNA and Cutaneous Wound Repair Biomolecular Research Reports, 2022 DOI Author Url Publisher Url Public Url
Bibby G, Krasniqi B, Reddy I, Sekar D, Ross K. 2021. Capturing the RNA castle: Exploiting MicroRNA inhibition for wound healing The Federation of European Biochemical Societies (FEBS) Journal, DOI Author Url Publisher Url Public Url
Ross K. 2021. MiR equal than others: MicroRNA enhancement for cutaneous wound healing Journal of Cellular Physiology, DOI Author Url Publisher Url Public Url
Ta Q, Ting J, Harwood S, Browning N, Simm A, Ross K, Olier I, Al-Kassas R. 2021. Chitosan nanoparticles for enhancing drugs and cosmetic components penetration through the skin European Journal of Pharmaceutical Sciences, DOI Author Url Publisher Url Public Url
Richardson A, Powell AK, Sexton DW, Parsons J, Reynolds N, Ross K. 2020. MicroRNA-184 Is Induced By Store-Operated Calcium Entry And Regulates Early Keratinocyte Differentiation Journal of Cellular Physiology, DOI Author Url Publisher Url Public Url
Richardson A, Owens DJ, Ross K. 2018. MicroRNA-184 and its lncRNA sponge uca1 are induced in wounded keratinocytes in a store-operated calcium entry-dependent manner. British Journal of Dermatology, DOI Author Url Publisher Url Public Url
Ross K. 2017. Towards topical microRNA-directed therapy for epidermal disorders Journal of Controlled Release, DOI Author Url Publisher Url Public Url
Journal article
Selvakumar SC, Preethi KA, Ross K, Sekar D. 2024. The emerging role of microRNA-based therapeutics in the treatment of preeclampsia Placenta, 158 :38-47 DOI Author Url Publisher Url Public Url
Ogiji ED, Aboheimed N, Ross K, Voller C, Siner R, Jensen RL, Jolly CE, Carr DF. 2024. Greater mechanistic understanding of the cutaneous pathogenesis of Stevens-Johnson syndrome/toxic epidermal necrolysis can shed light on novel therapeutic strategies: a comprehensive review Current Opinion in Allergy and Clinical Immunology, 24 :218-227 DOI Author Url Publisher Url Public Url
Ross K. 2024. Comment on Polak et al. Principles and Limitations of miRNA Purification and Analysis in Whole Blood Collected during Ablation Procedure from Patients with Atrial Fibrillation. J. Clin. Med. 2024, 13, 1898 Journal of Clinical Medicine, 13 :3671-3671 DOI Author Url Publisher Url
Gordon S, Layton AM, Fawcett SA, Ross K. 2024. A microRNA focus on acne Dermatology Reports, 16 DOI Author Url Publisher Url Public Url
Harland E, Alhusban D, Abdoubaki R, Marfing D, Simm A, McCloskey AP, Ehtezazi T, Ross K. 2023. A novel peptide for microRNA delivery to medulloblastoma cells Biomolecular Research Reports, 1 :1-11 Publisher Url Public Url
Dognini P, Chaudhry T, Scagnetti G, Assante M, Hanson GSM, Ross K, Giuntini F, Coxon CR. 2023. 5,10,15,20-Tetrakis(pentafluorophenyl)porphyrin as Functional Platform for Peptide Stapling and Multicyclisation Chemistry (Weinheim an der Bergstrasse, Germany), :e202301410 DOI Author Url Publisher Url Public Url
Abdellatif AAH, Scagnetti G, Younis MA, Bouazzaoui A, Tawfeek HM, Aldosari BN, Almurshedi AS, Alsharidah M, Rugaie OA, Davies MPA, Liloglou T, Ross K, Saleem I. 2023. Non-coding RNA-directed therapeutics in lung cancer: Delivery technologies and clinical applications Colloids and Surfaces B: Biointerfaces, 229 :1-17 DOI Author Url Publisher Url Public Url
Selvakumar SC, Preethi KA, Ross K, Tusubira D, Sekar D. 2023. MicroRNA-510-3p and Its Gene Network in the Disease Regulation of Preeclampsia: An Insilico Approach Journal of Biological Regulators and Homeostatic Agents, 37 :2291-2299 DOI Publisher Url Public Url
Sekar D, Tusubira D, Ross K. 2022. TDP-43 and NEAT long non-coding RNA: Roles in neurodegenerative disease Frontiers in Cellular Neuroscience, 16 DOI Author Url Publisher Url Public Url
Chaudhry T, Coxon CR, Ross K. 2022. Trading places: Peptide and small molecule alternatives to oligonucleotide-based modulation of microRNA expression Drug Discovery Today, 27 DOI Author Url Publisher Url Public Url
Preethi KA, Selvakumar SC, Ross K, Sekar D. 2022. Therapeutic aspect of microRNA inhibition in various types of hypertension and hypertensive complications Gene Reports, 29 :101676-101676 DOI Publisher Url Public Url
Fawcett SA, Al Kassas R, Dykes IM, Hughes AT, Ghali F, Ross K. 2022. A Time to Heal: MicroRNA and Circadian Dynamics in Cutaneous Wound Repair Clinical Science, 136 :579-597 DOI Author Url Publisher Url Public Url
Selvakumar SC, Preethi KA, Ross K, Tusubira D, Khan MWA, Mani P, Rao TN, Sekar D. 2022. CRISPR/Cas9 and next generation sequencing in the personalized treatment of Cancer Molecular Cancer, 21 DOI Author Url Publisher Url Public Url
Preethi KA, Selvakumar S, Ross K, Jayaraman S, Tusubira D, Sekar D. 2022. Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer Molecular Cancer, 21 DOI Author Url Publisher Url Public Url
Abdulazeez MA, Jasim HA, Bashir M, Ross K, Fatokun AA. 2022. Peristrophe bicalyculata (Retz) Nees contains principles that are cytotoxic to cancer cells and induce caspase-mediated, intrinsic apoptotic death through oxidative stress, mitochondrial depolarisation and DNA damage Biomedicine & Pharmacotherapy, 147 DOI Author Url Publisher Url Public Url
Dykes IM, Ross K. 2021. Restoring the Final Frontier: Exosomal MicroRNA and Cutaneous Wound Repair Biomolecular Research Reports, 2022 DOI Author Url Publisher Url Public Url
Bibby G, Krasniqi B, Reddy I, Sekar D, Ross K. 2021. Capturing the RNA castle: Exploiting MicroRNA inhibition for wound healing The Federation of European Biochemical Societies (FEBS) Journal, DOI Author Url Publisher Url Public Url
Ross K. 2021. MiR equal than others: MicroRNA enhancement for cutaneous wound healing Journal of Cellular Physiology, DOI Author Url Publisher Url Public Url
Ta Q, Ting J, Harwood S, Browning N, Simm A, Ross K, Olier I, Al-Kassas R. 2021. Chitosan nanoparticles for enhancing drugs and cosmetic components penetration through the skin European Journal of Pharmaceutical Sciences, DOI Author Url Publisher Url Public Url
Richardson A, Powell AK, Sexton DW, Parsons J, Reynolds N, Ross K. 2020. MicroRNA-184 Is Induced By Store-Operated Calcium Entry And Regulates Early Keratinocyte Differentiation Journal of Cellular Physiology, DOI Author Url Publisher Url Public Url
Sekar D, Johnson J, Biruntha M, Lakhmanan G, Gurunathan D, Ross K. 2019. Biological and Clinical Relevance of microRNAs in Mitochondrial Diseases DNA and Cell Biology, DOI Author Url Publisher Url Public Url
Brown P, Ross K, RELISH Consortium , Zhou Y. 2019. Large expert-curated database for benchmarking document similarity detection in biomedical literature search Database: the journal of biological databases and curation, DOI Author Url Publisher Url Public Url
Mohamed A, Pekoz AY, Ross K, Hutcheon GA, Saleem IY. 2019. Pulmonary delivery of Nanocomposite Microparticles (NCMPs) incorporating miR-146a for treatment of COPD. International Journal of Pharmaceutics, 569 DOI Author Url Publisher Url Public Url
Mohamed A, Kunda NK, Ross K, Hutcheon GA, Saleem IY. 2019. Polymeric Nanoparticles for the Delivery of miRNA to Treat Chronic Obstructive Pulmonary Disease (COPD). European Journal of Pharmaceutics and Biopharmaceutics, 136 :1-8 DOI Author Url Publisher Url Public Url
Richardson A, Muir L, Mousdell S, Sexton DW, Jones S, Howl J, Ross K. 2018. Modulation of mitochondrial activity in HaCaT keratinocytes by the cell penetrating peptide Z-Gly-RGD(DPhe)-mitoparan. BMC Research Notes, 11 DOI Author Url Publisher Url Public Url
Ross K. 2017. Towards topical microRNA-directed therapy for epidermal disorders Journal of Controlled Release, DOI Author Url Publisher Url Public Url
Farrer DJ, Roberts JC, Ross K. 2016. MicroRNA-9 represses sirtuin 1 (SIRT1) in human keratinocytes Scholars Bulletin, 2 :525-529 DOI Publisher Url Public Url
Roberts JC, Warren RB, Griffiths CEM, Ross K. 2013. Expression of microRNA-184 in keratinocytes represses argonaute 2. Journal of Cellular Physiology, 228 :2314-2323 DOI Publisher Url
Jans, R , Mottram, L , Johnson, DL , Brown, AM , Sikkink, S , Ross,K , Reynolds, NJ . 2012. Lysophosphatidic Acid Promotes Cell Migration through STIM1- and Orai1-Mediated Ca2+i Mobilization and NFAT2 Activation. Journal of Investigative Dermatology, 133 :793-802 DOI Author Url Publisher Url
Fearon P, Lonsdale-Eccles AA, Ross OK, Todd C, Sinha A, Allain F, Reynolds NJ. 2011. Keratinocyte Secretion of Cyclophilin B via the Constitutive Pathway Is Regulated through Its Cyclosporin-Binding Site. Journal of Investigative Dermatology, 131 :1085-1094 DOI Author Url Publisher Url
Ross OK, Parker G, Whitaker M, Reynolds MJ. 2008. Inhibition of calcium-independent phospholipase A impairs agonist-induced calcium entry in keratinocytes British Journal of Dermatology, 158 :31-37 DOI Author Url Publisher Url Public Url
Hampton P, Ross OK, Reynolds NJ. 2007. Increased nuclear beta-catenin in suprabasal involved psoriatic epidermis British Journal of Dermatology, 157 :1168-1177 DOI Author Url Publisher Url
Ross K, Whitaker M, Reynolds NJ. 2007. Agonist-induced Calcium Entry correlates with STIM1 translocation. Journal of Cellular Physiology, 211 :569-576 DOI Author Url Publisher Url
Hoogduijn MJ, Cemeli E, Ross K, Anderson, D , Thody AJ, Wood JM. 2004. Melanin Protects Melanocytes and Keratinocytes Against H2O2-induced DNA Strand Breaks Through its Ability to Bind Ca2+. Experimental Cell Research, 294 :60-67 DOI Author Url Publisher Url
Yang L, Ross K, Qwarnstrom EE. 2003. RelA Control Of IkBa Phosphorylation: A Positive Feedback Loop For High Affinity NF-kB Complexes. Journal of Biological Chemistry, 278 :30881-30888 DOI Author Url Publisher Url
Ross K, Yang L, Dower S, Volpe F, Guesdon F. 2002. Identification of Threonine 66 as a Functionally Critical Residue of the Interleukin-1 Receptor-associated Kinase (IRAK). Journal of Biological Chemistry, 277 :37414-37421 DOI Author Url Publisher Url
Other
Sekar D, Tusubira D, Ross K. 2022. Corrigendum: TDP-43 and NEAT long non-coding RNA: Roles in neurodegenerative disease, (Front. Cell. Neurosci, (2022), 16, (954912), 10.3389/fncel.2022.954912) Frontiers in Cellular Neuroscience, 16 DOI Author Url Publisher Url
Dataset
Richardson A, Owens D, Ross K. 2021. MicroRNA-184 and its lncRNA sponge uca1 are induced in wounded keratinocytes in a store-operated calcium entry-dependent manner. DOI Publisher Url Public Url
Ross K. MicroRNA Expression in Scarring Alopecia
Poster
Chaudhry T, Coxon C, Ross K. 2021. MicroRNA-21 Targeting Peptides: A Potential Approach To Cancer Therapy. RNA 2021 (Online conference)
Scagnetti G, Ross K, Saleem I. 2021. microRNA-184 mimic delivery via microfluidic-based chitosan nanoparticles: a potential tool to tackle cisplatin resistance in NSCLC RNA 2021 (Online conference)
Chaudhry T, Ross K, Coxon C. 2020. MicroRNA-21 Targeting Peptides: A Potential Approach to Cancer Therapy CEM-Teledyne Peptide Synthesis and Purification Meeting, Herriot-Watt University, Edinburgh, UK.
Scagnetti G, Ross K, Carini V, Davies, M , Liloglou T, Saleem I. 2019. Water-soluble Chitosan Nanoparticles Loaded with miRNA-mimics to overcome Cisplatin Resistance in Non-small Cell Lung Carcinoma EACR Nanotechnology in Cancer: Engineering for Oncology, Cambridge, UK.
Richardson A, Sexton D, Powell AK, Ross K. 2017. A store-operated calcium entry-dependent regulatory loop between nuclear factor of activated T-cells 1 and miR-184 in keratinocytes Non-Coding RNA: Recent Insights into the Mechanism of Action, Biochemical Society Conference, Edinburgh, UK.
Richardson A, Ross K. 2017. Conservation and number of microRNA-21 binding sites correlates with interferon gamma-dependent suppression of target transcripts Non-Coding RNA: Recent Insights into the Mechanisms of Action. A Biochemical Society Focused Meeting. Royal College of Surgeons of Edinburgh, Edinburgh, UK.
Richardson A, Sexton D, Powell AK, Ross K. 2016. Argonaute Expression in Psoriasis and Epidermal Keratinocytes. Inflammatory diseases - mechanisms and clinical perspectives, Maynooth University, Ireland. A Biochemical Society Focused Meeting.
Mohamed A, Ross K, Saleem IY, Hutcheon GA. 2016. Pulmonary Delivery of Therapeutic miR-146a Nanoparticles. AAPS National Biotechnology Conference, Boston, USA.
Mohamed A, Ross K, Saleem IY, Hutcheon GA. 2015. Polymeric Nanoparticles for the Pulmonary Delivery of miRNA to Treat Chronic Obstructive Pulmonary Disease (COPD). 42nd Annual Meeting & Exposition of the Controlled Release Society, Edinburgh.
Tusubira D, Wabinga H, Ross K, Masembe C. 2012. The Potential of Serum micro-RNAs in the Screening and early detection of Breast Cancer. Advanced Summer School on Nutrition and Disease: Biochemical and Molecular Insights. South Africa.
Coyne V, Ross K, Shriver Z, Wills B, Powell AK. 2012. Applying an HPLC structural glycomics strategy to investigate triggers of changes in HS structure. Biochemical Society/Royal Society of Chemistry workshop. London.
Coyne V, Ross K, Shriver Z, Wills B, Powell AK. 2012. Applying an HPLC structural glycomics strategy to investigate triggers of changes in HS structure Carbohydrate analysis and glycomics: where next? Biochemical Society/Royal Society of Chemistry workshop
Conference publication
Dognini P, Chaudhry T, Ross K, Coxon C, Giuntini F. 2021. Polyfluorinated Aromatic Porphyrin as a Photoactive Scaffold for Peptide Cyclisation 27–28 May 2021, MDPI: Basel, Switzerland, Proceedings of the First Canadian Peptide and Protein Community Virtual Symposium,, First Canadian Peptide and Protein Community Virtual Symposium DOI
Ross K, Richardson A. 2019. MicroRNA-184 - An Ally in Calcium Signalling in the Skin RNA 2019: The 24th Annual Meeting of the RNA Society, RNA 2019: The 24th Annual Meeting of the RNA Society Public Url
Richardson A, Ross K. 2017. Transforming Growth Factor Beta Induces MicroRNA-21 and TIMP-3 in Human Keratinocytes British Society for Investigative Dermatology Annual Meeting 176 :e66-e66 Publisher Url
Richardson A, Sexton D, Powell AK, Ross K. 2017. Defining the Role of Argonautes in Human Epidermal Keratinocytes British Society for Investigative Dermatology Annual Meeting 176 :e71-e71
Ross K, Richardson A, Tan TH, Roberts JC. 2016. Argonautes and the human keratinocyte: the microRNA connection. British Journal of Dermatology, British Skin Foundation, Skin Deep - 20 Years of Research, 20th Anniversary Conference 175 :61-61 DOI Author Url Publisher Url
Tan TH, Yesudian, PD, West, L, Al-Sharqi, A, Parslew R, Ross K. 2016. Evaluation of the relationship between aquaporin-9 and microRNA-205 expression in psoriatic epidermis. British Journal of Dermatology, British Association of Dermatologists 96th Annual Meeting 175 :52-52 DOI Publisher Url
Jans R, Mottram L, Johnson J, Brown AM, Sikkink S, Ross K, Reynolds NJ. 2012. Lysophosphatidic acid promotes keratinocyte migration through STIM1-regulated Orai1-Ca2+ channels and NFAT2 activation. Journal of Investigative Dermatology, 42nd Annual Meeting of the European Society for Dermatological Research (ESDR) 132 :S101-S101
Tusubira, D , Wabinga, H , Masembe, C , Ross, K . 2012. The Potential of Serum micro-RNAs in the Screening and early detection of Breast Cancer Advanced Summer School on Nutrition and Disease: Biochemical and Molecular Insights
Fearon P, Lonsdale-Eccles AA, Ross K, Todd C, Allain A, Reynolds NJ. 2009. Secretion of chemotactic cyclophilin B by keratinocytes is regulated through its cyclosporin binding site. Journal of Investigative Dermatology, 37th Annual Meeting of the European Society for Dermatological Research (ESDR 2007) 127 :S39-S39
Jans R, Brown AM, Ross K, Reynolds NJ. 2009. Lysophosphatidic acid-evoked calcium fluxes promote keratinocyte migration through Orai1, lipid rafts and NFAT. Journal of Investigative Dermatology, 69th Annual Meeting of the Society of Investigative Dermatology 129 :S90-S90 Publisher Url
Jans R, Brown A, Sikkink S, Ross K, Reynolds NJ. 2009. Lysophosphatidic acid-evoked calcium fluxes promote NFAT-mediated keratinocyte migration. British Journal of Dermatology, British Society for Investigative Dermatology Annual Meeting 160 :903-904
Milner S, Ross K, Reynolds NJ. 2009. Inhibition of store-operated calcium entry and STIM1 translocation by dithranol is dependent upon superoxide formation. British Journal of Dermatology, Annual Meeting of the British Society for Investigative Dermatology 160 :914-914
Jans R, Sikkink S, Flockhart RJ, Al-Daraji W, Brown AM, Ross K, Reynolds NJ. 2008. NFAT2 is involved in regulating keratinocyte proliferation and differentiation. Journal of Investigative Dermatology, International Investigative Dermatology Meeting 128 :S130-S130
Milner S, Ross K, Thody A, Reynolds NJ. 2008. The anti-psoriatic drug anthralin inhibits calcium release from the endoplasmic reticulum, store-operated calcium entry and the translocation of stromal interacting molecule 1 (STIM1). International Investigative Dermatology Meeting 128 :S134-S134
Milner S, Ross K, Thody T, Reynolds NJ. 2008. The anti-psoriatic drug dithranol inhibits agonist-induced calcium flux and the translocation of stromal-interacting molecule 1. British Journal of Dermatology, Annual Meeting of the British Society for Investigative Dermatology 158 :899-899
Jans R, Sikkink S, Flockhart R, Al-Daraji W, Brown AM, Ross K, Reynolds NJ. 2008. NFAT2 – a novel regulator of both keratinocyte proliferation and differentiation. British Journal of Dermatology, Annual Meeting of the British Society for Investigative Dermatology 158 :905-905
Fearon P, Lonsdale-Eccles AA, Ross K, Todd C, Allain A, Reynolds NJ. 2007. Secretion of chemotactic cyclophilin B by keratinocytes is regulated through its cyclosporin binding site Journal of Investigative Dermatology, 37th Annual Meeting of the European Society for Dermatological Research (ESDR 2007) 127 :S39-S39
Lonsdale-Eccles AA, Fearon P, Ross K, Allain F, Reynolds NJ. 2007. Location, mobility and secretion of cyclophilin B in keratinocytes is regulated through its ciclosporin A binding site. British Journal of Dermatology, Annual Meeting of the British Society for Investigative Dermatology 156 :1097-1097
Hampton PJ, Ross K, Reynolds NJ. 2007. Lithium inhibits the transcriptional activation, mRNA and protein expression of transglutaminase 1 in keratinocytes. British Society for Investigative Dermatology 156 :1106-1106
Ross K, Reynolds NJ. 2006. Regulation of calcium entry in Keratinocytes by calcium-independent PLA2 and STIM1. Journal of Investigative Dermatology, 36th Annual European Society for Dermatological Research 126 :S94-S94
Ross K, Reynolds NJ. 2005. Inhibition of calcium-independent phospholipase A impairs lysophosphatidic acid-induced calcium entry in keratinocytes. British Journal of Dermatology, British Society for Investigative Dermatology meeting 152 :836-836
Ross K, Whitaker M, Reynolds NJ. 2004. Agonist Induced Ca2+ oscillations and Ca2+ entry in Keratinocytes. Journal of Investigative Dermatology, 34th European Society for Dermatological Research meeting 123 :pA60-pA60
Thesis/Dissertation
Al Lawati M. 2021. Molecular background of serological D negative phenotype in the Omani population Ross K, Louhelainen J, Lowe G, Flegel B. Public Url
Richardson A. 2019. MicroRNA-184: A Multifaceted Regulator of Epidermal Keratinocyte Biology Ross K, Powell A, Sexton D. Public Url
Mohamed AA. MicroRNA Nanocarriers for the Treatment of Chronic Obstructive Pulmonary Disease Saleem I, Hutcheon G, Ross K. Public Url
Editorial/letter to the editor
Richardson A, Owens DJ, Ross K. 2018. MicroRNA-184 and its lncRNA sponge uca1 are induced in wounded keratinocytes in a store-operated calcium entry-dependent manner. British Journal of Dermatology, DOI Author Url Publisher Url Public Url
Report
Wise A, Ross K. 2016. Biochemical Society Summer Vacation Studentship Report Amino Acid Signaling in Skin: SLC38A9 Expression in Keratinocytes Author Url
Research Grants Awarded:
Industrial Biotechnology Innovation Catalyst, Illuminating Intercellular RNA transmission, Iain Dykes, Grant value (£): 10000, Duration of research project: 6 months. 2024
Alopecia UK, Uncovering MicroRNA Targets in Scarring Alopecia, Grant value (£): 1000. 2019
British Skin Foundation, Scarring Alopecia: Are Rogue Small RNAs to Blame?, Matthew Harries, Grant value (£): 10000. 2017
British Skin Foundation, British Skin Foundation: Inhibiting microRNA-21 expression in psoriasis with a curcumin analogue. Role: PI £10,000 09/2015–02/2017, Grant value (£): 10000. 2015
British Skin Foundation, Defining the Role of the MicroRNA-184:Argonaute 2 axis in Psoriasis, Nicholas J Reynolds, Newcastle University, Grant value (£): £81,000, Duration of research project: 3 years. 2014
Biochemical Society, Analysis of serum microRNA, Grant value (£): 1000. 2010
Liverpool John Moores University Studentship (MPhil), MicroRNA Expression and Function in the Skin, Grant value (£): 45,000, Duration of research project: 18 months. 2009
British Skin Foundation, Does interleukin-22-dependent upregulation of microRNA contribute to the psoriatic phenotype?, Grant value (£): 70K, Duration of research project: 18 months. 2008
North Eastern Skin Research Fund, Regulation of keratinocyte microRNA by S100 proteins, Grant value (£): 3820. 2008
The Physiological Society, Analysis of iPLA2 mobility in keratinocytes, Grant value (£): £1200, Duration of research project: 2 months. 2006
Medical Research Council, Computational reconstruction of a TGFβ-Smad network., Nicholas Monk, University of Sheffield, Grant value (£): 84,487, Duration of research project: 1 year. 2006
Newcastle Healthcare Charity Award, Regulation of Calcium-sensing Receptor Expression in Keratinocytes and Psoriasis, Professor Nick Reynolds, Grant value (£): 39,692, Duration of research project: 1 year. 2005
Conference presentation:
Towards MicroRNA-based Therapeutics for Wound Repair, European Wound Management Association, London, Keynote Presentation for the European Tissue Repair Society Session. 2024
Towards MicroRNA Nanotherapeutics for Medulloblastoma, North West Cancer Research Symposium, Lancaster University, Poster presentation. 2023
MicroRNA-29 Family and Circadian Regulation of Cutaneous Wound Repair, 28th International Conference of the RNA Society, Singapore, Poster presentation. 2023
Once Upon a Time in Africa: Diversity, Equity and Inclusion Panel, 28th International Conference of the RNA Socierty, Singapore, Oral presentation. 2023
Circadian Dynamics in an In Vitro Model of Cutaneous Wound Repair, UK Clock Club Spring Meeting, University of Surrey, Poster presentation. 2023
Translational Prospects for MicroRNA-184 in Cutaneous Wound Repair, 4th Annual RNA Therapeutics conference, Online, Oral presentation. 2022
Translational Prospects for MicroRNA-184 in Cutaneous Wound Repair. June 2022, 4th Annual RNA Therapeutics conference, Online, Oral presentation. 2022
Ultraviolet radiation and trichostatin A modulate miR-9 expression in human keratinocytes, Big Roles for Small RNAs, 2016, University of East Anglia, Oral presentation. 2016
Other Professional Activity:
Chair of the RNA Society Diversity, Equity and Inclusion Committee. 2024
Other invited event:
African Life Science RNA Salon, Online, Keynote speaker at the inaugural African Life Science RNA Salon webinar. 2023
Liverpool Glioblastoma Workshop, Cedar House, University of Liverpool, Towards RNA Nanotherapies for Glioblastoma. 2023
Pint of Science, Liverpool, RNA Everywhere All At Once. 2023
Invited Presentation, Manchester RNA Salon Online, Towards RNA-directed Therapeutics (Flash Talk). 2020
Invited Presentation, Online; University of Tartu, Estonia, From Inflammation to Migration: Studies on MicroRNA-184 in the Skin. 2020
LJMU Christmas Research Cafe, Everyman Theatre, Liverpool, A Tale of Three Cities: My Journey into Skin Biology. 2019
Invited Presentation, Open University, Milton Keynes, From Inflammation to Migration: Studies on microRNA-184 in the Skin. 2019
Dermatology Seminar, Broadgreen Hospital, Guardians of the Cutaneous Galaxy: microRNAs and Inflammatory Skin Disease. 2017
Dermatology Seminar, Broadgreen Hospital, Presentation on MicroRNA in skin disorders. 2014
miRNAs, siRNAs and non-coding RNAs in health and disease, Manchester, Conference presentation. 2010
Institute for Health Research (IHR) Conference, Liverpool, Conference presentation. 2010
Award:
Biochemical Society General Travel Grant 2023, Biochemical Society. 2023
RNA Society Research Presentation Fellowship 2023, RNA Society. 2023
Travel Award, Physiological Society. 2019
RNA 2019 Travel Award, The RNA Society. 2019
Crucible Award, National Endowment for Science, Technology and Arts (NESTA). 2007
MRC Discipline Hopping Award, Medical Research Council. 2006
Media Coverage:
British Skin Foundation (opens in a new tab) 2022
British Skin Foundation (opens in a new tab)
External PGR examinations performed:
University of Sheffield, PhD, Identification and Characterisation of Novel Melanocyte Autoantigens in Alopecia Areata. 2020
University of Tartu, Estonia, PhD, Potential Therapeutic Approaches for Modulation of Inflammatory Response pathways. 2020
Durham University, PhD, Exploring the Impact of Mechanical Transduction During Hair Follicle Compression and In Providing Cellular Differentiation and Proliferation. 2019
University of Liverpool, Wan Mustapa., PhD, ATP Release in the Epidermis. 2014
Membership of professional bodies:
Member, RNA Society, http://www.rnasociety.org/. 2017
Member, British Hair and Nail Society, https://bhns.org.uk/. 2016
Member, European Tissue Repair Society, http://www.etrs.org/. 2016
Affiliate Member, Royal Society of Chemistry, http://www.rsc.org/. 2016
Member, Physiological Society, http://www.physoc.org/. 2005
Member, Biochemical Society, http://www.biochemistry.org/. 2005
Member, British Society for Investigative Dermatology, http://bsid.org.uk/. 2005
Teaching qualification:
Postgraduate Certificate for Learning and Teaching in Higher Education. 2013
Fellowships:
Fellow of the Higher Education Academy, Higher Education Academy.